Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM80980
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
IC50
8320±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM80980
Synonyms:
MLS001081319 | SMR000708704 | [4-(3,5-dimethylpiperidin-1-yl)carbonylphenyl]-phenyl-methanone | [4-(3,5-dimethylpiperidine-1-carbonyl)phenyl]-phenyl-methanone | [4-(3,5-dimethylpiperidine-1-carbonyl)phenyl]-phenylmethanone | [4-[(3,5-dimethyl-1-piperidinyl)-oxomethyl]phenyl]-phenylmethanone | cid_24981653
Type:
Small organic molecule
Emp. Form.:
C21H23NO2
Mol. Mass.:
321.4128
SMILES:
CC1CC(C)CN(C1)C(=O)c1ccc(cc1)C(=O)c1ccccc1
Structure:
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