Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50026657
Substrate
n/a
Meas. Tech.
ChEBML_28518
IC50
37000±n/a nM
Citation
 Glennon, RA; Tejani-Butt, SM; Padgett, W; Daly, JW Mesoionic xanthine analogues: antagonists of adenosine receptors. J Med Chem 27:1364-7 (1984) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50026657
Synonyms:
1-Cyclopropylmethyl-3-ethyl-1,9a-dihydro-9-thia-1,4a-diaza-fluorene-2,4-dione | CHEMBL29416
Type:
Small organic molecule
Emp. Form.:
C16H18N2O2S
Mol. Mass.:
302.391
SMILES:
CCC1C(=O)N2C(Sc3ccccc23)N(CC2CC2)C1=O
Structure:
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