Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50030217
Substrate
n/a
Meas. Tech.
ChEMBL_195687 (CHEMBL800604)
IC50
720±n/a nM
Citation
 Mohan, P; Loya, S; Avidan, O; Verma, S; Dhindsa, GS; Wong, MF; Huang, PP; Yashiro, M; Baba, M; Hizi, A Synthesis of naphthalenesulfonic acid small molecules as selective inhibitors of the DNA polymerase and ribonuclease H activities of HIV-1 reverse transcriptase. J Med Chem 37:2513-9 (1994) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50030217
Synonyms:
CHEMBL313213 | Hexadecanoic acid 1-hexadecanoylamino-4-sulfo-naphthalen-2-yl ester
Type:
Small organic molecule
Emp. Form.:
C42H69NO6S
Mol. Mass.:
716.065
SMILES:
CCCCCCCCCCCCCCCC(=O)Nc1c(OC(=O)CCCCCCCCCCCCCCC)cc(c2ccccc12)S(O)(=O)=O
Structure:
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