Reaction Details Report a problem with these data
Target
SPRY domain-containing SOCS box protein 2
Ligand
BDBM50532317
Substrate
n/a
Meas. Tech.
ChEMBL_1922843 (CHEMBL4425799)
Kd
465±n/a nM
Citation
Harjani, JR; Yap, BK; Leung, EW; Lucke, A; Nicholson, SE; Scanlon, MJ; Chalmers, DK; Thompson, PE; Norton, RS; Baell, JB Design, Synthesis, and Characterization of Cyclic Peptidomimetics of the Inducible Nitric Oxide Synthase Binding Epitope That Disrupt the Protein-Protein Interaction Involving SPRY Domain-Containing Suppressor of Cytokine Signaling Box Protein (SPSB) 2 and Inducible Nitric Oxide Synthase. J Med Chem 59:5799-809 (2016) [PubMed] Article
More Info.:
Target
Name:
SPRY domain-containing SOCS box protein 2
Synonyms:
Gene-rich cluster protein C9 | Grcc9 | SPRY domain-containing SOCS box protein 2 | SPSB2_MOUSE | SSB-2 | Spsb2 | Ssb2
Type:
PROTEIN
Mol. Mass.:
28943.57
Organism:
Mus musculus
Description:
ChEMBL_109468
Residue:
264
Sequence:
MGQTALARGSSSTPTSQALYSDFSPPEGLEELLSAPPPDLVAQRHHGWNPKDCSENIDVKEGGLCFERRPVAQSTDGVRGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQADHYAALLGSNSESWGWDIGRGKLYHQSKGLEAPQYPAGPQGEQLVVPERLLVVLDMEEGTLGYSIGGTYLGPAFRGLKGRTLYPSVSAVWGQCQVRIRYMGERRVEEPQSLLHLSRLCVRHALGDTRLGQISTLPLPPAMKRYLLYK