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Target
Galectin-7
Ligand
BDBM50273581
Substrate
n/a
Meas. Tech.
ChEMBL_1925943 (CHEMBL4429015)
Kd
1700±n/a nM
Citation
 Rajput, VK; MacKinnon, A; Mandal, S; Collins, P; Blanchard, H; Leffler, H; Sethi, T; Schambye, H; Mukhopadhyay, B; Nilsson, UJ A Selective Galactose-Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model. J Med Chem 59:8141-7 (2016) [PubMed]  Article 
Target
Name:
Galectin-7
Synonyms:
Gal-7 | Galectin-7 | LEG7_MOUSE | Lgals7
Type:
PROTEIN
Mol. Mass.:
15176.05
Organism:
Mus musculus
Description:
ChEMBL_118893
Residue:
136
Sequence:
MSATHHKTSLPQGVRVGTVMRIRGLVPDQAGRFHVNLLCGEEQGADAALHFNPRLDTSEVVFNTKQQGKWGREERGTGIPFQRGQPFEVLLIATEEGFKAVVGDDEYLHFHHRLPPARVRLVEVGGDVQLHSLNIF
  
Inhibitor
Name:
BDBM50273581
Synonyms:
CHEMBL444662 | N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihydroxy-6-(hydroxymethyl)-4-(naphthalene-2-amido)oxan-2-yl]sulfanyl}-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]naphthalene-2-carboxamide
Type:
Small organic molecule
Emp. Form.:
C34H36N2O10S
Mol. Mass.:
664.722
SMILES:
OC[C@H]1O[C@@H](S[C@@H]2O[C@H](CO)[C@H](O)[C@H](NC(=O)c3ccc4ccccc4c3)[C@H]2O)[C@H](O)[C@@H](NC(=O)c2ccc3ccccc3c2)[C@H]1O |r|
Structure:
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