Reaction Details Report a problem with these data
Target
Protein tyrosine phosphatase type IVA 3
Ligand
BDBM396097
Substrate
n/a
Meas. Tech.
ChEMBL_2109175 (CHEMBL4817850)
IC50
20±n/a nM
Citation
 Lin, L; Lu, L; Yuan, C; Wang, A; Zhu, M; Fu, X; Xing, S The dual inhibition against the activity and expression of tyrosine phosphatase PRL-3 from a rhodanine derivative. Bioorg Med Chem Lett 41:0 (2021) [PubMed]  Article 
Target
Name:
Protein tyrosine phosphatase type IVA 3
Synonyms:
PRL3 | PTP4A3 | Protein-tyrosine phosphatase 4A3 | TP4A3_HUMAN
Type:
PROTEIN
Mol. Mass.:
19546.22
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1461022
Residue:
173
Sequence:
MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
  
Inhibitor
Name:
BDBM396097
Synonyms:
US10308663, JMS-631-053
Type:
Small organic molecule
Emp. Form.:
C13H8N2O2S
Mol. Mass.:
256.28
SMILES:
N=C1c2sc(cc2C(=O)NC1=O)-c1ccccc1
Structure:
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