Reaction Details Report a problem with these data
Target
14 kDa phosphohistidine phosphatase
Ligand
BDBM50442875
Substrate
n/a
Meas. Tech.
ChEMBL_2212573 (CHEMBL5125522)
Ki
90000±n/a nM
Citation
 McCullough, BS; Wang, H; Barrios, AM Inhibitor Screen Identifies Covalent Inhibitors of the Protein Histidine Phosphatase PHPT1. ACS Med Chem Lett 13:1198-1201 (2022) [PubMed] 
Target
Name:
14 kDa phosphohistidine phosphatase
Synonyms:
3.9.1.3 | PHP | PHP14 | PHP14_HUMAN | PHPT1 | Phosphohistidine phosphatase 1
Type:
PROTEIN
Mol. Mass.:
13830.85
Organism:
Homo sapiens
Description:
ChEMBL_120739
Residue:
125
Sequence:
MAVADLALIPDVDIDSDGVFKYVLIRVHSAPRSGAPAAESKEIVRGYKWAEYHADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQHAISTEKIKAKYPDYEVTWANDGY
  
Inhibitor
Name:
BDBM50442875
Synonyms:
NORSTICTIC ACID
Type:
Small organic molecule
Emp. Form.:
C18H12O9
Mol. Mass.:
372.2825
SMILES:
Cc1cc(O)c(C=O)c2Oc3c4C(O)OC(=O)c4c(O)c(C)c3OC(=O)c12
Structure:
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