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Target
Mu-type opioid receptor
Ligand
BDBM50203829
Substrate
n/a
Meas. Tech.
ChEMBL_425708 (CHEMBL913690)
IC50
16±n/a nM
Citation
 Fichna, J; do-Rego, JC; Chung, NN; Lemieux, C; Schiller, PW; Poels, J; Broeck, JV; Costentin, J; Janecka, A Synthesis and characterization of potent and selective mu-opioid receptor antagonists, [Dmt(1), D-2-Nal(4)]endomorphin-1 (Antanal-1) and [Dmt(1), D-2-Nal(4)]endomorphin-2 (Antanal-2). J Med Chem 50:512-20 (2007) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50203829
Synonyms:
CHEMBL375068 | Dmt-Pro-Trp-D-1-Nal-NH2
Type:
Small organic molecule
Emp. Form.:
C40H44N6O5
Mol. Mass.:
688.8146
SMILES:
Cc1cc(C[C@H](N)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@H](Cc2cccc3ccccc23)C(N)=O)cc(C)c1O
Structure:
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