Reaction Details Report a problem with these data
Target
Group IID secretory phospholipase A2
Ligand
BDBM50263051
Substrate
n/a
Meas. Tech.
ChEMBL_489273 (CHEMBL990829)
IC50
>1600±n/a nM
Citation
 Oslund, RC; Cermak, N; Gelb, MH Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2. J Med Chem 51:4708-14 (2008) [PubMed]  Article 
Target
Name:
Group IID secretory phospholipase A2
Synonyms:
PA2GD_MOUSE | Pla2a2 | Pla2g2d | Splash
Type:
PROTEIN
Mol. Mass.:
16175.77
Organism:
Mus musculus
Description:
ChEMBL_489273
Residue:
144
Sequence:
MRLALLCGLLLAGITATQGGLLNLNKMVTHMTGKKAFFSYWPYGCHCGLGGKGQPKDATDWCCQKHDCCYAHLKIDGCKSLTDNYKYSISQGTIQCSDNGSWCERQLCACDKEVALCLKQNLDSYNKRLRYYWRPRCKGKTPAC
  
Inhibitor
Name:
BDBM50263051
Synonyms:
2-(1-(2-amino-2-oxoacetyl)-2-(isobutyl)-3-(ophenylbenzyl)indolizin-8-yloxy)acetic acid | CHEMBL478820
Type:
Small organic molecule
Emp. Form.:
C29H28N2O5
Mol. Mass.:
484.543
SMILES:
CC(C)Cc1c(Cc2ccccc2-c2ccccc2)n2cccc(OCC(O)=O)c2c1C(=O)C(N)=O
Structure:
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