Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50277192
Substrate
n/a
Meas. Tech.
ChEMBL_540514 (CHEMBL1031455)
EC50
120±n/a nM
Citation
 Goodman, AJ; Ajello, CW; Worm, K; Le Bourdonnec, B; Savolainen, MA; O'Hare, H; Cassel, JA; Stabley, GJ; Dehaven, RN; Labuda, CJ; Koblish, M; Little, PJ; Brogdon, BL; Smith, SA; Dolle, RE CB2 selective sulfamoyl benzamides: optimization of the amide functionality. Bioorg Med Chem Lett 19:309-13 (2008) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50277192
Synonyms:
4-(5-(4-(cyclohexylmethyl)thiazol-2-yl)-2-methylphenylsulfonyl)morpholine | CHEMBL474896
Type:
Small organic molecule
Emp. Form.:
C21H28N2O3S2
Mol. Mass.:
420.589
SMILES:
Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nc(CC2CCCCC2)cs1
Structure:
Search PDB for entries with ligand similarity: