Reaction Details Report a problem with these data
Target
Phenylethanolamine N-methyltransferase
Ligand
BDBM50023309
Substrate
n/a
Meas. Tech.
ChEBML_152426
Ki
33100±n/a nM
Citation
 Grunewald, GL; Sall, DJ; Monn, JA Conformational and steric aspects of the inhibition of phenylethanolamine N-methyltransferase by benzylamines. J Med Chem 31:433-44 (1988) [PubMed]  Article 
Target
Name:
Phenylethanolamine N-methyltransferase
Synonyms:
Noradrenaline N-methyltransferase | PNMT | PNMT_BOVIN | PNMTase
Type:
Enzyme
Mol. Mass.:
30916.97
Organism:
Bovine
Description:
n/a
Residue:
283
Sequence:
MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRCLAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGAFDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVSAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVREALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
  
Inhibitor
Name:
BDBM50023309
Synonyms:
1-Methyl-1,2,3,4-tetrahydro-isoquinoline | 1-methyl-1,2,3,4-tetrahydroisoquinoline | CHEMBL95456
Type:
Small organic molecule
Emp. Form.:
C10H13N
Mol. Mass.:
147.2169
SMILES:
CC1NCCc2ccccc12
Structure:
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