Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50377706
Substrate
n/a
Meas. Tech.
ChEMBL_479927 (CHEMBL929250)
Ki
33±n/a nM
Citation
 Worm, K; Zhou, QJ; Saeui, CT; Green, RC; Cassel, JA; Stabley, GJ; DeHaven, RN; Conway-James, N; LaBuda, CJ; Koblish, M; Little, PJ; Dolle, RE Sulfamoyl benzamides as novel CB2 cannabinoid receptor ligands. Bioorg Med Chem Lett 18:2830-5 (2008) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50377706
Synonyms:
CHEMBL256110
Type:
Small organic molecule
Emp. Form.:
C22H30N2O4S
Mol. Mass.:
418.55
SMILES:
Cc1ccc(cc1S(=O)(=O)N1CCOCC1)C(=O)NC1C2CC3CC(C2)CC1C3 |TLB:18:19:21:25.23.24,THB:23:22:19:25.24.26,23:24:21.22.28:19,26:24:21:28.27.19,26:27:21:25.23.24,(25.81,-25.08,;25.81,-26.62,;24.48,-27.39,;24.48,-28.93,;25.82,-29.71,;27.16,-28.93,;27.15,-27.38,;28.48,-26.61,;29.26,-27.94,;27.71,-25.28,;29.81,-25.83,;31.15,-26.59,;32.48,-25.81,;32.47,-24.27,;31.13,-23.51,;29.8,-24.29,;25.82,-31.25,;24.48,-32.01,;27.15,-32.02,;27.19,-33.56,;25.99,-34.46,;24.26,-34.26,;25.48,-35.21,;25.88,-36.67,;27.5,-36.72,;26.4,-35.81,;28.74,-35.82,;28.36,-34.36,;26.76,-34.26,)|
Structure:
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