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Target
D-amino-acid oxidase
Ligand
BDBM50427212
Substrate
n/a
Meas. Tech.
ChEMBL_938788 (CHEMBL2327932)
IC50
>10000000±n/a nM
Citation
 Katane, M; Osaka, N; Matsuda, S; Maeda, K; Kawata, T; Saitoh, Y; Sekine, M; Furuchi, T; Doi, I; Hirono, S; Homma, H Identification of novel D-amino acid oxidase inhibitors by in silico screening and their functional characterization in vitro. J Med Chem 56:1894-907 (2013) [PubMed]  Article 
Target
Name:
D-amino-acid oxidase
Synonyms:
D-amino-acid oxidase (DAAO) | DAAO | DAMOX | DAO | OXDA_HUMAN
Type:
Homodimer
Mol. Mass.:
39476.06
Organism:
Homo sapiens (Human)
Description:
P14920
Residue:
347
Sequence:
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
  
Inhibitor
Name:
BDBM50427212
Synonyms:
(2S,3R)-2,3-Dihydroxysuccinic Acid | CHEMBL225983 | Meso-Tartrate
Type:
Small organic molecule
Emp. Form.:
C4H6O6
Mol. Mass.:
150.0868
SMILES:
O[C@@H]([C@@H](O)C(O)=O)C(O)=O |r|
Structure:
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