Reaction Details Report a problem with these data
Target
Lipoxygenase
Ligand
BDBM32020
Substrate
n/a
Meas. Tech.
ChEMBL_1437404 (CHEMBL3386626)
IC50
28000±n/a nM
Citation
 Pavic, K; Perkovic, I; Cindric, M; Pranjic, M; Martin-Kleiner, I; Kralj, M; Schols, D; Hadjipavlou-Litina, D; Katsori, AM; Zorc, B Novel semicarbazides and ureas of primaquine with bulky aryl or hydroxyalkyl substituents: synthesis, cytostatic and antioxidative activity. Eur J Med Chem 86:502-14 (2014) [PubMed]  Article 
Target
Name:
Lipoxygenase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
1886.07
Organism:
Glycine max
Description:
ChEMBL_103841
Residue:
18
Sequence:
PNSEEGLTCRGIPNSISI
  
Inhibitor
Name:
BDBM32020
Synonyms:
4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol | 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol | 4-[4-[3,4-bis(oxidanyl)phenyl]-2,3-dimethyl-butyl]benzene-1,2-diol | BDBM166684 | CHEMBL52 | LOX inhibitor, N/A | MLS000069451 | NORDIHYDROGUAIARETIC ACID | Nordihydroguaiaretic acid (NDGA) | SMR000059049 | US10857082, Compound 2.18 | cid_4534
Type:
Small organic molecule
Emp. Form.:
C18H22O4
Mol. Mass.:
302.3649
SMILES:
CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1
Structure:
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