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Target
Transducer protein HtrVI
Ligand
BDBM86441
Substrate
n/a
Ki
1000±n/a nM
Comments
PDSP_3924
Citation
 Kimura, Y; Hatanaka, K; Naitou, Y; Maeno, K; Shimada, I; Koakutsu, A; Wanibuchi, F; Yamaguchi, T Pharmacological profile of YM348, a novel, potent and orally active 5-HT2C receptor agonist. Eur J Pharmacol 483:37-43 (2004) [PubMed]  Article 
Target
Name:
Transducer protein HtrVI
Synonyms:
5-HT6 | HTR6 | Htr6 transducer
Type:
Enzyme Catalytic Domain
Mol. Mass.:
83828.60
Organism:
Halobacterium salinarum R1
Description:
5-HT6 HTR6 0::Q9HRA1
Residue:
789
Sequence:
MSDGITGALRNAASVVAPDAIRRRFGAKFAVAFIVVLVVIAGAGVFAFQSTETTVEHQTTRQLAESNQLEADAIGAWMEQQRTHARSVSQDEALRDDRRAAPYILLKDQLLPADVVSMHLVNETRGTVVASTELAIEGRSLAELDAPWTTAAVPEGPGNDSAVWATEQSYRSPVLNDEPVMAFASSVPKREGAHLVVVTRIQPQVDRLSDANSTRRTTILNTGDEPVLDSNSRFDAGALTDSIAAVRNDTTAATTTVSNGRVYALSATPHTDWVTVTSVDTGEAFAVRDTVGQTVTVLVVLAVISLAIVGIALGRHTVTPLKRLRNRAQDIESGTFDVDLSTRRIDEVGRLYGSFDDMRVSLQDRIQEAEAAVEEANAAKAEAEELRTDAEDAQAEAERAKATAEAASERLQERAADYSEVMQAVADGDLTERLDEDADEEAMRAVATEFNAMLDGLEATIAQVAGFADEVADETLQVATGAEEIETTSQTVSERIQEIADGAIQQHDDLERAAGEMDELSASIQEVAASSATVAETAADAVERGEAGRDAAESAIDDMAEIESLSADAVDQILALQERMSDIGDIIEFITDIAEQTNMLALNANIEAARADKDGDGFAVVANEVKDLAEETKQAAADIESEIQAVQAETDETVADIRATSEHIDDGVSTVERAAAAIEDTVDAIEDANHGIQEISDATEDQADATQSVVRRVDDVADISQHVTEDAEQVSAAAEEQSASVAEIARSADDLRDRADALATTVNQFETRADADEPDADTTVDASADDTGD
  
Inhibitor
Name:
BDBM86441
Synonyms:
CAS_3045225 | NSC_3045225 | YM348
Type:
Small organic molecule
Emp. Form.:
C14H17N3O
Mol. Mass.:
243.3043
SMILES:
CCc1cc2c(ccc3cnn(CC(C)N)c23)o1
Structure:
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