Reaction Details Report a problem with these data
Target
Tegument protein VP16
Ligand
BDBM87254
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)
IC50
>35903±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay (2012)[AID] 
Target
Name:
Tegument protein VP16
Synonyms:
Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16
Type:
PROTEIN
Mol. Mass.:
54325.13
Organism:
HHV-1
Description:
EBI_100271
Residue:
490
Sequence:
MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAALFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYVPERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALYRYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILWAAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIREHLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMREHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSLGDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFTDALGIDEYGG
  
Inhibitor
Name:
BDBM87254
Synonyms:
4-(2-indolin-1-yl-2-keto-ethyl)thieno[3,2-b]pyrrole-5-carboxylic acid ethyl ester | 4-[2-(2,3-Dihydro-indol-1-yl)-2-oxo-ethyl]-4H-thieno[3,2-b]pyrrole-5-carboxylic acid ethyl ester | 4-[2-(2,3-dihydroindol-1-yl)-2-oxoethyl]-5-thieno[3,2-b]pyrrolecarboxylic acid ethyl ester | MLS000033904 | SMR000008303 | cid_648405 | ethyl 4-[2-(2,3-dihydroindol-1-yl)-2-oxidanylidene-ethyl]thieno[3,2-b]pyrrole-5-carboxylate | ethyl 4-[2-(2,3-dihydroindol-1-yl)-2-oxoethyl]thieno[3,2-b]pyrrole-5-carboxylate
Type:
Small organic molecule
Emp. Form.:
C19H18N2O3S
Mol. Mass.:
354.423
SMILES:
CCOC(=O)c1cc2sccc2n1CC(=O)N1CCc2ccccc12
Structure:
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