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Target
Prostaglandin E2 receptor EP2 subtype
Ligand
BDBM204964
Substrate
n/a
Meas. Tech.
Cellular Functional Assay
EC50
27±n/a nM
Citation
 Feutrill, J; Leriche, C; Middlemiss, D Aniline derivatives, their preparation and their therapeutic application US Patent  US9249085 Publication Date 2/2/2016 
Target
Name:
Prostaglandin E2 receptor EP2 subtype
Synonyms:
PE2R2_HUMAN | PGE receptor EP2 subtype | PTGER2 | Prostaglandin E2 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP4 subtype | Prostanoid EP2 Receptor
Type:
Enzyme
Mol. Mass.:
39775.71
Organism:
Homo sapiens (Human)
Description:
P43116
Residue:
358
Sequence:
MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGSGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
  
Inhibitor
Name:
BDBM204964
Synonyms:
US9249085, I(x)
Type:
Small organic molecule
Emp. Form.:
C22H15F3N2O3
Mol. Mass.:
412.3613
SMILES:
OC(=O)COc1ccc(F)c(NCc2cc(cc(c2)-c2cccc(F)c2)C#N)c1F
Structure:
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