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Target
Serine protease 1
Ligand
BDBM50024354
Substrate
n/a
Meas. Tech.
Human Trypsin Assay
pH
8.2±n/a
Ki
>20000±n/a nM
Comments
extracted
Citation
 Chen, S; Ding, Z; Gong, G; Yan, X; Huang, W; Guo, F; Duan, B; Gao, R; Zhou, P; Lu, X; Dong, G Preparation method for benzoxazoleoxazine ketone compound and intermediate and crystal form thereof US Patent  US10106557 Publication Date 10/23/2018 
Target
Name:
Serine protease 1
Synonyms:
Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1
Type:
Enzyme
Mol. Mass.:
26557.80
Organism:
Human
Description:
P07477
Residue:
247
Sequence:
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS
  
Inhibitor
Name:
BDBM50024354
Synonyms:
CHEMBL3330444 | US10106557, Compound 2
Type:
Small organic molecule
Emp. Form.:
C21H20ClN3O5S
Mol. Mass.:
461.919
SMILES:
[H][C@@]12COc3cc(ccc3N1C(=O)O[C@H]2CNC(=O)c1ccc(Cl)s1)N1CCCCC1=O |r|
Structure:
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