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Target
Mu-type opioid receptor
Ligand
BDBM425916
Substrate
n/a
Meas. Tech.
In-Vitro Efficacy of mPEG-O-Opioid Conjugates to Inhibit cAMP Formation
EC50
22083±n/a nM
Citation
 Riggs-Sauthier, J; Deng, B; Riley, TA Oligomer-opioid agonist conjugates US Patent  US10512644 Publication Date 12/24/2019 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM425916
Synonyms:
US10512644, Compound alpha-6-mPEG4-O-Codeine
Type:
Small organic molecule
Emp. Form.:
C27H41NO7
Mol. Mass.:
491.6169
SMILES:
COCCOCCOCCOCCO[C@H]1C=CC2[C@@H](Cc3ccc(OC)c4O[C@@H]1[C@]2(C)c34)N(C)C |r,c:15|
Structure:
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