Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM507041
Substrate
n/a
Ki
23±n/a nM
Citation
 Martin, SF; Sahn, JJ; Hodges, TR Piperazinyl norbenzomorphan compounds and methods for using the same US Patent  US11046670 Publication Date 6/29/2021 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Homo sapiens (Human)
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM507041
Synonyms:
US11046670, Compound 30
Type:
Small organic molecule
Emp. Form.:
C28H35N3O2
Mol. Mass.:
445.5964
SMILES:
[#6]\[#6](-[#6])=[#6]\[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccc2-[#6@H]-3-[#6]-[#6@@H](-[#7](-[#6]-[#6]-3)-[#6](=O)-[#8]-[#6]-c3ccccc3)-c2c1 |r,TLB:21:18:14.31:16,32:31:20.18.19:16,THB:13:14:20.18.19:16|
Structure:
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