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Target
Bromodomain testis-specific protein [287-359]
Ligand
BDBM205429
Substrate
n/a
Meas. Tech.
Plate-Based Time-Resolved Fluorescence Energy Transfer (TR-FRET) Assays
IC50
217±n/a nM
Citation
 Zhou, J; Brasier, AR; Tian, B; Liu, Z; Chen, H; Rytting, E Inhibitors of bromodomain-containing protein 4 (BRD4) US Patent  US11117865 Publication Date 9/14/2021 
Target
Name:
Bromodomain testis-specific protein [287-359]
Synonyms:
BRDT | BRDT_HUMAN | Bromodomain testis-specific protein (BRDT)(BD2)
Type:
n/a
Mol. Mass.:
8713.30
Organism:
Homo sapiens (Human)
Description:
Q58F21[287-359]
Residue:
73
Sequence:
KHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVV
  
Inhibitor
Name:
BDBM205429
Synonyms:
(R)-JQ1 (3) | US10407441, Compound (R)-JQ1 | US10925881, Name (R)-JQ1 | US11028051, Cmpd (+)-JQ1 | US11117865, Compound JQ1 | US11306105, Compound JQ1 | US11406645, Compound JQ1 | US11542273, Example (+)-JQ1 | US11890288, Compound (+)-JQ1 | US9320741, (R)-JQ1
Type:
Small organic molecule
Emp. Form.:
C23H25ClN4O2S
Mol. Mass.:
456.988
SMILES:
Cc1nnc2[C@@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14|
Structure:
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