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Target
Probable G-protein coupled receptor 139
Ligand
BDBM263509
Substrate
n/a
Meas. Tech.
Radioligand Assay
Ki
117±n/a nM
Citation
 Hitchcock, S; Lam, B; Monenschein, H; Reichard, H 4-oxo-3,4-dihydro-1,2,3-benzotriazine modulators of GPR139 US Patent  US11173161 Publication Date 11/16/2021 
Target
Name:
Probable G-protein coupled receptor 139
Synonyms:
G(q)-coupled orphan receptor GPRg1 | G-protein coupled receptor 139 | G-protein-coupled receptor PGR3 | GP139_HUMAN | GPR139 | GPRG1 | GPRG1 | PGR3 | Probable G-protein coupled receptor 139
Type:
PROTEIN
Mol. Mass.:
40700.34
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109920
Residue:
353
Sequence:
MEHTHAHLAANSSLSWWSPGSACGLGFVPVVYYSLLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADILVLFFIVFVDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVHHVLIWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRTMAAATLKAFFKCQKQPVQFYTNHNFSITSSPWISPANSHCIKMLVYQYDKNGKPIKVSP
  
Inhibitor
Name:
BDBM263509
Synonyms:
US10561662, Example 81 | US11173161, EX 81 | US9556130, test 81 | n-(2-chloro-4-methoxyphenethyl)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)acetamide
Type:
Small organic molecule
Emp. Form.:
C18H17ClN4O3
Mol. Mass.:
372.806
SMILES:
COc1ccc(CCNC(=O)Cn2nnc3ccccc3c2=O)c(Cl)c1
Structure:
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