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Target
N-formyl peptide receptor 2
Ligand
BDBM526315
Substrate
n/a
Meas. Tech.
FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays
EC50
0.350±n/a nM
Citation
 Wurtz, NR; Shirude, PS; Viet, AQ Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists US Patent  US11186544 Publication Date 11/30/2021 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM526315
Synonyms:
US11186544, Example 211
Type:
Small organic molecule
Emp. Form.:
C25H25ClN4O5S
Mol. Mass.:
529.008
SMILES:
CS(=O)(=O)Nc1ccccc1-c1ccc(cc1)N1C[C@H](O)C[C@@H](NC(=O)Nc2ccc(Cl)cc2)C1=O |r|
Structure:
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