Reaction Details Report a problem with these data
Target
Dynein light chain 2, cytoplasmic
Ligand
BDBM528572
Substrate
n/a
Meas. Tech.
Biochemical Assay
IC50
290±n/a nM
Citation
 Kapoor, TM; Asano, M; Aso, K; Foley, MA; Fukase, Y; Furukawa, H; Hirata, Y; Takashima, S; Okawa, T; Tanaka, Y; Yoshitomi, Y Pyrazoloquinazolinone antitumor agents US Patent  US11192893 Publication Date 12/7/2021 
Target
Name:
Dynein light chain 2, cytoplasmic
Synonyms:
8 kDa dynein light chain b | DLC2 | DLC8b | DYL2_HUMAN | DYNLL2 | Dynein light chain LC8-type 2
Type:
Protein
Mol. Mass.:
10351.24
Organism:
Human
Description:
Q96FJ2
Residue:
89
Sequence:
MSDRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG
  
Inhibitor
Name:
BDBM528572
Synonyms:
US11192893, Example 12
Type:
Small organic molecule
Emp. Form.:
C20H12BrClN4O
Mol. Mass.:
439.692
SMILES:
Clc1ccc(cc1)C1(CC1)c1nn2c([nH]c3ccc(Br)cc3c2=O)c1C#N
Structure:
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