Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM530549
Substrate
n/a
EC50
870±n/a nM
Citation
 L., PH; A., JJ; V., DS AMINOIMIDAZOLE FPR2 AGONISTS WIPO 0:0 (2022) [PubMed] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM530549
Synonyms:
WO2022076764, Example 78
Type:
Small organic molecule
Emp. Form.:
C24H18F4N4O3
Mol. Mass.:
486.4183
SMILES:
COc1cc(F)c(c(F)c1)-n1cc(Cc2ccccn2)nc1NC(=O)c1ccc(OC(F)F)cc1 |(1.23,-8.54,;2.26,-7.39,;1.79,-5.93,;.28,-5.61,;-.2,-4.14,;-1.7,-3.82,;.83,-3,;2.34,-3.32,;3.37,-2.18,;2.82,-4.78,;.36,-1.53,;-1.1,-1.06,;-1.1,.48,;-2.35,1.39,;-3.76,.76,;-3.92,-.77,;-5.33,-1.4,;-6.57,-.49,;-6.41,1.04,;-5,1.66,;.36,.96,;1.26,-.29,;2.8,-.29,;3.57,1.04,;2.8,2.38,;5.12,1.04,;5.88,-.29,;7.42,-.29,;8.2,1.04,;9.74,1.04,;10.51,2.38,;9.74,3.71,;12.05,2.38,;7.42,2.38,;5.88,2.38,)|
Structure:
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