Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM532352
Substrate
n/a
Meas. Tech.
Competitive Radioligand Binding Assay 2
Ki
2.10±n/a nM
Citation
 Rishton, GM; Look, GC; Catalano, SM Compositions for treating neurodegenerative diseases US Patent  US11214540 Publication Date 1/4/2022 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM532352
Synonyms:
US11214540, Example 10
Type:
Small organic molecule
Emp. Form.:
C17H26ClNO
Mol. Mass.:
295.847
SMILES:
COC1CCN(CCC(C)(C)c2ccc(Cl)cc2)CC1
Structure:
Search PDB for entries with ligand similarity: