Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM532367
Substrate
n/a
Meas. Tech.
Competitive Radioligand Binding Assay 2
Ki
10.00±n/a nM
Citation
 Rishton, GM; Look, GC; Catalano, SM Compositions for treating neurodegenerative diseases US Patent  US11214540 Publication Date 1/4/2022 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM532367
Synonyms:
US11214540, Example 25
Type:
Small organic molecule
Emp. Form.:
C17H26FNO
Mol. Mass.:
279.3928
SMILES:
CC(CC(C)(C)c1ccc(F)cc1)N1CCC(O)CC1
Structure:
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