Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM540271
Substrate
n/a
Meas. Tech.
Measurement of Activity of GPR120 Agonist (Cell-Based Assay)
EC50
<200±n/a nM
Citation
 Kim, YK; Park, SY; Joo, HW; Choi, ES; Paek, SY; Kang, SW; Kim, BG; Lee, CS; Kim, SW; Lee, SD Biaryl derivative as GPR120 agonist US Patent  US11261186 Publication Date 3/1/2022 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM540271
Synonyms:
US11261186, Example 198
Type:
Small organic molecule
Emp. Form.:
C19H22F2N2O2S
Mol. Mass.:
380.452
SMILES:
CC(C)Sc1ncccc1-c1cc(F)c(N(C)CCCC(O)=O)c(F)c1
Structure:
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