Reaction Details Report a problem with these data
Target
Bromodomain testis-specific protein [22-138]
Ligand
BDBM543776
Substrate
n/a
Meas. Tech.
AlphaLisa Assay
IC50
292±n/a nM
Citation
 Upadhayaya, RS; Kethiri, R; Madan, S; Rajaiah, SK Fused pyrimidine compounds as BRD4 and JAK2 dual inhibitors and methods for use thereof US Patent  US11279703 Publication Date 3/22/2022 
Target
Name:
Bromodomain testis-specific protein [22-138]
Synonyms:
BRDT | BRDT_HUMAN | Bromodomain testis-specific protein (BRDT)(BD1)
Type:
n/a
Mol. Mass.:
13948.58
Organism:
Homo sapiens (Human)
Description:
Q58F21[22-138]
Residue:
117
Sequence:
TKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQ
  
Inhibitor
Name:
BDBM543776
Synonyms:
US11279703, TABLE 6.366 | US11279703, TABLE 6.388
Type:
Small organic molecule
Emp. Form.:
C27H29F2N7O2S
Mol. Mass.:
553.627
SMILES:
CC(C)(C)S(=O)(=O)Nc1cc(ccc1F)-n1ccc2cnc(Nc3cc4CC5CNCCN5c4c(F)c3)nc12
Structure:
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