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Target
D(3) dopamine receptor
Ligand
BDBM554491
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
0.341±0.0312 nM
Citation
 Newman, AH; Kumar, V; Shaik, AB Dopamine D3 receptor selective antagonists/partial agonists and uses thereof US Patent  US11337971 Publication Date 5/24/2022 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM554491
Synonyms:
US11337971, Compound 28
Type:
Small organic molecule
Emp. Form.:
C27H34ClN4O2
Mol. Mass.:
482.037
SMILES:
CCc1cc(Cl)c(OC)c(c1)N1CCN(CCCCCNC(=O)c2cc3ccccc3n2)CC1
Structure:
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