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Target
2-Hydroxyacid oxidase 1
Ligand
BDBM560926
Substrate
n/a
Meas. Tech.
In-Vitro Human Glycolate Oxidase (hGOX) Assay
IC50
4.00±n/a nM
Citation
 Keller, BT; Talley, JJ Compounds and methods for treating oxalate-related diseases US Patent  US11389456 Publication Date 7/19/2022 
Target
Name:
2-Hydroxyacid oxidase 1
Synonyms:
GOX1 | HAO1 | HAOX1_HUMAN | Hydroxyacid oxidase 1
Type:
PROTEIN
Mol. Mass.:
40927.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_71275
Residue:
370
Sequence:
MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVRKNPLAVSKI
  
Inhibitor
Name:
BDBM560926
Synonyms:
5-(4-ethynylphenoxy)- 1H-1,2,3-triazole-4- carboxylic acid | US11389456, Ex. No. I-297
Type:
Small organic molecule
Emp. Form.:
C10H7N3O
Mol. Mass.:
185.1821
SMILES:
C#Cc1ccc(Oc2cnn[nH]2)cc1
Structure:
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