Reaction Details Report a problem with these data
Target
Large envelope protein
Ligand
BDBM576348
Substrate
n/a
Meas. Tech.
PHH Natural Infection Assay
IC50
2805±n/a nM
Citation
 Hongying, Y; Bo, Z; Xiufang, Z AROMATIC BRIDGED RING AMIDE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION WIPO 0:0 (2022) [PubMed] 
Target
Name:
Large envelope protein
Synonyms:
HBSAG_HBVD3 | S
Type:
n/a
Mol. Mass.:
42772.52
Organism:
Hepatitis B virus
Description:
P03138
Residue:
389
Sequence:
MGQNLSTSNPLGFFPDHQLDPAFRANTANPDWDFNPNKDTWPDANKVGAGAFGLGFTPPHGGLLGWSPQAQGILQTLPANPPPASTNRQSGRQPTPLSPPLRNTHPQAMQWNSTTFHQTLQDPRVRGLYFPAGGSSSGTVNPVLTTASPLSSIFSRIGDPALNMENITSGFLGPLLVLQAGFFLLTRILTIPQSLDSWWTSLNFLGGTTVCLGQNSQSPTSNHSPTSCPPTCPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLIPGSSTTSTGPCRTCMTTAQGTSMYPSCCCTKPSDGNCTCIPIPSSWAFGKFLWEWASARFSWLSLLVPFVQWFVGLSPTVWLSVIWMMWYWGPSLYSILSPFLPLLPIFFCLWVYI
  
Inhibitor
Name:
BDBM576348
Synonyms:
WO2022112205, Example 4
Type:
Small organic molecule
Emp. Form.:
C20H17ClN2O4S
Mol. Mass.:
416.878
SMILES:
Clc1ccc2oc(nc2c1)C12CC(C1)(C2)NC(=O)c1ccc(o1)S(=O)C1CC1
Structure:
Search PDB for entries with ligand similarity: