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Target
Cation-dependent mannose-6-phosphate receptor
Ligand
BDBM582011
Substrate
n/a
Meas. Tech.
General M6PR Binding Assay
IC50
300±n/a nM
Citation
 Bradley, BB; Thomas, EJ; K., PG; G., LJ; D., TE M6PR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES WIPO 0:0 (2023) [PubMed] 
Target
Name:
Cation-dependent mannose-6-phosphate receptor
Synonyms:
M6PR | MPR46 | MPRD | MPRD_HUMAN
Type:
PROTEIN
Mol. Mass.:
30989.41
Organism:
Homo sapiens (Human)
Description:
ChEMBL_492874
Residue:
277
Sequence:
MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSFESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIMLIYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACSPEISHLSVGSILLVTFASLVAVYVVGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM
  
Inhibitor
Name:
BDBM582011
Synonyms:
WO2023288015, Compound P2
Type:
Small organic molecule
Emp. Form.:
C25H33N6O9P
Mol. Mass.:
592.5381
SMILES:
O[C@@H]1[C@@H](CCP(O)(O)=O)O[C@H](Oc2ccc(NC(=O)NCCCCc3cn(nn3)-c3cccnc3)cc2)[C@@H](O)[C@H]1O |r|
Structure:
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