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Target
Calcium/calmodulin-dependent protein kinase type 1D
Ligand
BDBM585147
Substrate
n/a
Meas. Tech.
Biochemical CaMK1D Enzymatic Activity Assay
IC50
27.0±n/a nM
Citation
 Fischer, P; Fromont, C; Stevenson, B; Butterworth, S; Iacobini, G; Greco, G; Sanz, MG; Jones, H; Kaur, D Kinase inhibitors US Patent  US11530193 Publication Date 12/20/2022 
Target
Name:
Calcium/calmodulin-dependent protein kinase type 1D
Synonyms:
CAMK1D | CAMKID | CaM kinase I delta | KCC1D_HUMAN
Type:
PROTEIN
Mol. Mass.:
42916.83
Organism:
Homo sapiens (Human)
Description:
ChEMBL_586559
Residue:
385
Sequence:
MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCLAPSTLCSFISSSSGVSGVGAERRPRPTTVTAVHSGSK
  
Inhibitor
Name:
BDBM585147
Synonyms:
US11530193, Example 58
Type:
Small organic molecule
Emp. Form.:
C24H29N7O
Mol. Mass.:
431.5334
SMILES:
CC(C)c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(n1)-c1ccccc1 |r|
Structure:
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