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Target
Interleukin-4
Ligand
BDBM589754
Substrate
n/a
IC50
0.650±n/a nM
Citation
 Strohbach, JW; Akama, T; Blakemore, DC; Jacobs, RT; Jones, P; Limburg, DC; Oderinde, MS; Perry, MA; Plattner, JJ; Torella, RF; Zhou, Y; Yeoh, TY Substituted 1,2-oxaborolan-2-ols as PDE4 inhibitors US Patent  US11559538 Publication Date 1/24/2023 
Target
Name:
Interleukin-4
Synonyms:
B-cell stimulatory factor 1 | BSF-1 | Binetrakin | IL-4 | IL4 | IL4_HUMAN | Lymphocyte stimulatory factor 1 | Pitrakinra
Type:
Protein
Mol. Mass.:
17502.15
Organism:
Human
Description:
P05112
Residue:
153
Sequence:
MGLTSQLLPPLFFLLACAGNFVHGHKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGLNSCPVKEANQSTLENFLERLKTIMREKYSKCSS
  
Inhibitor
Name:
BDBM589754
Synonyms:
US11559538, Example 17 | US11559538, Example 50
Type:
Small organic molecule
Emp. Form.:
C18H20BF2NO4
Mol. Mass.:
363.164
SMILES:
CCCOc1cc(ccc1OC(F)F)-c1cncc(c1)C1COB(O)C1
Structure:
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