Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM590785
Substrate
n/a
Meas. Tech.
CB1 and CB2 Receptor Binding Assay
IC50
0.800±n/a nM
Citation
 Elzein, E; Liu, J Cannabinoid receptor type 2 (CB2) modulators and uses thereof US Patent  US11564928 Publication Date 1/31/2023 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM590785
Synonyms:
6-(4-fluorophenyl)-1-(2-morpholinoethyl)-2- oxo-N-(spiro[3.3]heptan-2-yl)-1,2-dihydro- 1,8-naphthyridine-3-carboxamide | US11564928, Compound 32
Type:
Small organic molecule
Emp. Form.:
C28H31FN4O3
Mol. Mass.:
490.5691
SMILES:
Fc1ccc(cc1)-c1cnc2n(CCN3CCOCC3)c(=O)c(cc2c1)C(=O)NC1CC2(CCC2)C1
Structure:
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