Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 5
Ligand
BDBM594032
Substrate
n/a
Meas. Tech.
Fluorescence Detection (FLIPR) Assay
EC50
>10000±n/a nM
Citation
 Ji, Q; Zhang, X; Du, Z; Gong, L; Wang, L; Gao, C; Du, M Amino alcohol derivative, pharmaceutical composition and application thereof US Patent  US11584726 Publication Date 2/21/2023 
Target
Name:
Sphingosine 1-phosphate receptor 5
Synonyms:
EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41796.42
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
398
Sequence:
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
  
Inhibitor
Name:
BDBM594032
Synonyms:
(S)-(2-amino-7-(5-(3,4-diethoxyphenyl)-1,3,4-oxadiazol-2-yl)-1,2,3,4-tetrahydronaphthalen-2-yl)methanol | US11584726, Example 13
Type:
Small organic molecule
Emp. Form.:
C23H27N3O4
Mol. Mass.:
409.4782
SMILES:
CCOc1ccc(cc1OCC)-c1nnc(o1)-c1ccc2CC[C@@](N)(CO)Cc2c1 |r|
Structure:
Search PDB for entries with ligand similarity: