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Target
Lymphocyte cytosolic protein 2
Ligand
BDBM598031
Substrate
n/a
Meas. Tech.
TBD
IC50
48.0±n/a nM
Citation
 Liang, J; Mendonca, RV; Siu, M; Tellis, J; Wang, W; Wei, B; Chan, B; Choo, EF; Drobnick, J; Gazzard, LJ; Heffron, T 8-aminoisoquinoline compounds and uses thereof US Patent  US11612606 Publication Date 3/28/2023 
Target
Name:
Lymphocyte cytosolic protein 2
Synonyms:
LCP2 | LCP2_HUMAN | SH2 domain-containing leukocyte protein of 76 kDa | SLP-76 tyrosine phosphoprotein | SLP76
Type:
Protein
Mol. Mass.:
60184.91
Organism:
Human
Description:
Q13094
Residue:
533
Sequence:
MALRNVPFRSEVLGWDPDSLADYFKKLNYKDCEKAVKKYHIDGARFLNLTENDIQKFPKLRVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGSRYQCTLTHAAGYP
  
Inhibitor
Name:
BDBM598031
Synonyms:
(R)-Tetrahydrofuran-3-yl(8-amino-7- | US11612606, Compound 403a
Type:
Small organic molecule
Emp. Form.:
C22H22FN5O4
Mol. Mass.:
439.4396
SMILES:
Cc1c2NCCOc2ncc1-c1cc2cc(NC(=O)O[C@@H]3CCOC3)ncc2c(N)c1F |r|
Structure:
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