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Target
Transcription initiation factor TFIID subunit 1 [1504-1635]
Ligand
BDBM310914
Substrate
n/a
Meas. Tech.
TAF1-BD2 TR-FRET Binding Assay
IC50
350±n/a nM
Citation
 Albrecht, BK; Bellon, SF; Burdick, DJ; Cote, A; Crawford, T; Dakin, LA; Hsiao-Wei Tsui, V; Hewitt, MC; LeBlanc, Y; Magnuson, SR; Nasveschuk, CG; Romero, AF; Tang, Y; Taylor, AM; Wang, S Therapeutic compounds and uses thereof US Patent  US10150767 Publication Date 12/11/2018 
Target
Name:
Transcription initiation factor TFIID subunit 1 [1504-1635]
Synonyms:
BA2R | CCG1 | CCGS | TAF1 | TAF1-BD2 (11 1504-1635) | TAF1-BD2 (aa 1504-1635) | TAF1_HUMAN | TAF2A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
15296.09
Organism:
Homo sapiens (Human)
Description:
P21675[1504-1635]
Residue:
132
Sequence:
QVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAALEEAELESLD
  
Inhibitor
Name:
BDBM310914
Synonyms:
6-methyl-4-[4-(morpholine-4-carbonyl)phenyl]-1H-pyrrolo[2,3-c]pyridin-7-one | US10150767, Example 30
Type:
Small organic molecule
Emp. Form.:
C19H19N3O3
Mol. Mass.:
337.3725
SMILES:
Cn1cc(-c2ccc(cc2)C(=O)N2CCOCC2)c2cc[nH]c2c1=O
Structure:
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