Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM250131
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay on Rat TAAR1
Ki
2981±n/a nM
Citation
 Groebke Zbinden, K; Norcross, R; Pfileger, P Substituted benzamides US Patent  US11697636 Publication Date 7/11/2023 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rattus norvegicus (Rat)
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM250131
Synonyms:
US10501411, Example 41 | US11697636, Example 41 | US9452980, 41
Type:
Small organic molecule
Emp. Form.:
C18H20N2O
Mol. Mass.:
280.3642
SMILES:
CC1(CCNC1)c1ccc(NC(=O)c2ccccc2)cc1
Structure:
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