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Target
Hemagglutinin
Ligand
BDBM611056
Substrate
n/a
Meas. Tech.
Biological Activity
IC50
7.00±n/a nM
Citation
 Jonckers, TH; McGowan, DC; Guilllemont, J; Cooymans, LP; Embrechts, WC; Buyck, CF; Balemans, WM; Raboisson, PJ Heterocyclic indoles for use in influenza virus infection US Patent  US10626108 Publication Date 4/21/2020 
Target
Name:
Hemagglutinin
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
38441.02
Organism:
n/a
Description:
P12590
Residue:
344
Sequence:
MKAKLLVLLCAFTATDADTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCRLKGIAPLQLGNCSIAGWILGNPECESLFSKKSWSYIAETPNSENGTCYPGYFADYEELREQLSSVSSFERFEIFPKESSWPNHTVTKGVTAACSHKGKSSFYRNLLWLTEKNGSYPNLSKSYVNNKEKEVLVLWGVHHPSNIGDQRAIYHTENAYVSVVSSHYNRRFTPEIAKRPKVRGQEGRINYYWTLLEPEDTIIFEANGNLIAPWYAFALSRGFGSGIITSNASMDECDAKCQTPQGAINSSLPFQNVHPVTIGECPKYVRSTKLRMVTGLRNIPSIQSR
 
Inhibitor
Name:
BDBM611056
Synonyms:
US10626108, Compound 36
Type:
Small organic molecule
Emp. Form.:
C22H19F3N8O3
Mol. Mass.:
500.4333
SMILES:
OC(=O)c1nc(nc(N[C@@H]2CCC[C@@H](C2)NC(=O)c2cnn[nH]2)c1F)-c1c[nH]c2c(F)cc(F)cc12 |r,$;;;;;;;;HN;;;;;;;HN;;;;;;;;;;;;;;;;;;;;$|
Structure:
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