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Target
Flavin reductase (NADPH)
Ligand
BDBM50548283
Substrate
n/a
Meas. Tech.
Enzyme Activity Assay
Kd
70.0±20 nM
Citation
 Ryu, K; Kim, M; Griesinger, C; Lee, D Method of increasing platelet counts of a subject US Patent  US11744839 Publication Date 9/5/2023 
Target
Name:
Flavin reductase (NADPH)
Synonyms:
1.3.1.24 | 1.5.1.30 | BLVRB | BLVRB_HUMAN | BVR-B | Biliverdin reductase B | Biliverdin-IX beta-reductase | FLR
Type:
PROTEIN
Mol. Mass.:
22123.63
Organism:
Homo sapiens
Description:
ChEMBL_100283
Residue:
206
Sequence:
MAVKKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAADVDKTVAGQDAVIVLLGTRNDLSPTTVMSEGARNIVAAMKAHGVDKVVACTSAFLLWDPTKVPPRLQAVTDDHIRMHKVLRESGLKYVAVMPPHIGDQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTDEYDGHSTYPSHQYQ
  
Inhibitor
Name:
BDBM50548283
Synonyms:
C. i. mordant yellow 5 | Dipentum | Olsalazine | US11744839, Compound of formula 2
Type:
Small organic molecule
Emp. Form.:
C14H10N2O6
Mol. Mass.:
302.239
SMILES:
OC(=O)c1cc(ccc1O)\N=N\c1ccc(O)c(c1)C(O)=O
Structure:
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