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Target
N-formyl peptide receptor 2
Ligand
BDBM620557
Substrate
n/a
Meas. Tech.
cAMP Assay
EC50
0.200±n/a nM
Citation
 Shirude, PS; Rachamreddy, CR; Baligar, V; Seshadri, B; Madduri, SR; Kick, EK; Wurtz, NR OXOPYRROLIDINE UREA FPR2 AGONISTS US Patent  US20230303513 Publication Date 9/28/2023 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM620557
Synonyms:
US20230303513, Example 16 | US20230303513, Example 5
Type:
Small organic molecule
Emp. Form.:
C30H33ClN4O5
Mol. Mass.:
565.06
SMILES:
COCCn1cccc(N2C[C@H]([C@H](NC(=O)NC3CCc4cc(Cl)ccc4C3)C2=O)c2ccc(OC)cc2)c1=O |r|
Structure:
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