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Target
G-protein coupled receptor 52
Ligand
BDBM622917
Substrate
n/a
Meas. Tech.
Homogeneous Time-Resolved Fluorescence (HTRF) Assay
EC50
5.00±n/a nM
Citation
 Gerlach, K; Semple, G; Xiong, Y; Bertani, B; Ferrara, M; Fossati, G; Hobson, S; Lessel, UF; Runge, F; Mueller-Vieira, U; Wippich, J Substituted 3-phenoxyazetidin-1-yl-pyrazines US Patent  US11780827 Publication Date 10/10/2023 
Target
Name:
G-protein coupled receptor 52
Synonyms:
GPR52 | GPR52_HUMAN | Probable G-protein coupled receptor 52
Type:
PROTEIN
Mol. Mass.:
41366.15
Organism:
Homo sapiens (Human)
Description:
ChEMBL_108391
Residue:
361
Sequence:
MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI
  
Inhibitor
Name:
BDBM622917
Synonyms:
US11780827, Example 15
Type:
Small organic molecule
Emp. Form.:
C19H15F3N6O2
Mol. Mass.:
416.3566
SMILES:
Cc1cc(NC(=O)c2nccnc2N2CC(C2)Oc2cc(F)c(F)c(F)c2)cnn1
Structure:
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