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Target
N-formyl peptide receptor 2
Ligand
BDBM632092
Substrate
n/a
Meas. Tech.
FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays
EC50
0.100±n/a nM
Citation
 Shirude, PS; Rachamreddy, CR; Chattopadhyay, AK; Seshadri, B; Baligar, V; Madduri, SR; Kick, EK; Wurtz, NR OXOPYRROLIDINE FPR2 AGONISTS US Patent  US20230348426 Publication Date 11/2/2023 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM632092
Synonyms:
US20230348426, Example 362 | US20230348426, Example 581
Type:
Small organic molecule
Emp. Form.:
C27H26ClF2N3O5
Mol. Mass.:
545.962
SMILES:
COc1cc(F)c([C@@H]2CN(C(=O)[C@H]2NC(=O)c2ccc(Cl)cc2)c2c(C)ccn(CC(C)O)c2=O)c(F)c1
Structure:
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