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Target
Calcitonin gene-related peptide 1
Ligand
BDBM312052
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
0.100±n/a nM
Citation
 Christopher, JA; Congreve, MS; Bucknell, SJ; Deflorian, F; Pickworth, M; Mason, JS CGRP receptor antagonists US Patent  US10166226 Publication Date 1/1/2019 
Target
Name:
Calcitonin gene-related peptide 1
Synonyms:
CALC1 | CALCA | CALCA_HUMAN | CGRP | Calcitonin gene-related peptide (CGRP alpha) | Calcitonin gene-related peptide 1
Type:
Enzyme
Mol. Mass.:
13902.80
Organism:
Homo sapiens (Human)
Description:
P06881
Residue:
128
Sequence:
MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFGRRRRDLQA
  
Inhibitor
Name:
BDBM312052
Synonyms:
N-{(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(5-methyl-4H-1,2,4-triazol-3-yl)-1,4'-bipiperidin-1'-yl]-1-oxopropan-2-yl}-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide | US10166226, Example 8
Type:
Small organic molecule
Emp. Form.:
C39H48N10O3
Mol. Mass.:
704.8636
SMILES:
Cc1nnc([nH]1)C1CCN(CC1)C1CCN(CC1)C(=O)[C@@H](Cc1cc(C)c2[nH]ncc2c1)NC(=O)N1CCC(CC1)c1cc2ccccc2[nH]c1=O |r|
Structure:
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