Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM642633
Substrate
n/a
Meas. Tech.
Adenosine Receptor Binding Assay
Ki
456±n/a nM
Citation
 COHEN, CJ; KLUGE, AF; RAY, SS; HUTCHINSON, JH ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE US Patent  US20230416245 Publication Date 12/28/2023 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM642633
Synonyms:
US20230416245, Compound 71
Type:
Small organic molecule
Emp. Form.:
C14H16Cl2N4O2
Mol. Mass.:
343.208
SMILES:
CCNc1c(Cl)c(Cl)nc2n(cnc12)[C@@H]1[C@H]2C[C@H]2[C@@H](O)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: