Reaction Details Report a problem with these data
Target
Biofilm regulatory protein A
Ligand
BDBM50026472
Substrate
n/a
Meas. Tech.
Inhibition of the activity of Gtfs determined by Zymographic Assay
IC50
>500000±n/a nM
Citation
 Velu, SE; Wu, H; Zhang, Q; Nijampatnam, B Streptococcus mutans glucosyl transferase inhibitors for dental caries therapy US Patent  US11866416 Publication Date 1/9/2024 
Target
Name:
Biofilm regulatory protein A
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
43911.21
Organism:
Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Description:
Q8DVR0
Residue:
406
Sequence:
MKIGKKILIMLVTIFLTSLVALGVYATSIYNFSLGEFSKTFKDYGTGSGKDVIADEKPFSILLMGVDTGSSERTSKWEGNSDSMILVTVNPKTKKTTMTSLERDILVKLSGSKTNDQTGYDAKLNAAYAAGGAKMAIMTVQDMLDIKIDKYVQINMEGLVQLVDAVGGITVTNHFDFPISIEEHEPEFTASVEPGTHKINGEQALVYSRMRYDDPDGDYGRQKRQREVISKVLKKILALDSVSKYRKILSAVSKNMQTNIEISSSTIPKLLGYSDALKSIRTYQLKGEGTTIDGGSYQLVTSKELLKAQNRIKGQLGLKKSTAENLKTTASLYENFYGGDTSIYDSSSSASDYSSSGNYSGSSSDYGSSSSYGSNSSSGSSSDYSGQNSYNQGNYQQPAAGTGIGN
  
Inhibitor
Name:
BDBM50026472
Synonyms:
(CH3)2SO | (methanesulfinyl)methanedimethyl sulfoxide | CHEMBL504 | DIMETHYL SULFOXIDE | Dimethylsulfoxid | S(O)Me2 | US11866416, Compound DMSO | dimethyl sulfur oxide | dimethyl sulphoxide | dmso | methylsulfinylmethane | sulfinylbis(methane)
Type:
Small organic molecule
Emp. Form.:
C2H6OS
Mol. Mass.:
78.133
SMILES:
CS(C)=O
Structure:
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