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Target
Monoacylglycerol lipase ABHD6 [33-337]
Ligand
BDBM645029
Substrate
n/a
Meas. Tech.
Evaluation of ABHD6 Enzyme Inhibitory Activity Assay
IC50
<1.000±n/a nM
Citation
 YOSHIDA, A; HYAKUTAKE, R; NAGASHIMA, N; MISU, R; MORI, S ABHD6 ANTAGONIST US Patent  US20240010658 Publication Date 1/11/2024 
Target
Name:
Monoacylglycerol lipase ABHD6 [33-337]
Synonyms:
Monoacylglycerol lipase ABHD6 (33-337)
Type:
Enzyme
Mol. Mass.:
34939.75
Organism:
Homo sapiens (Human)
Description:
Q9BV23[33-337]
Residue:
305
Sequence:
ALIRIYYWYWRRTLGMQVRYVHHEDYQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDDLSIDGQVKRIHQFVECLKLNKKPFHLVGTSMGGQVAGVYAAYYPSDVSSLCLVCPAGLQYSTDNQFVQRLKELQGSAAVEKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNNFYRKLFLEIVSEKSRYSLHQNMDKIKVPTQIIWGKQDQVLDVSGADMLAKSIANCQVELLENCGHSVVMERPRKTAKLIIDFLASVHNTDNNKKLD
  
Inhibitor
Name:
BDBM645029
Synonyms:
US20240010658, Example 10
Type:
Small organic molecule
Emp. Form.:
C17H18BrFN4OS
Mol. Mass.:
425.318
SMILES:
Cc1ccc(s1)C(=O)N1C[C@@H]2CC[C@@H](Nc3ccc(Br)nn3)[C@]2(F)C1 |r|
Structure:
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