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Target
G-protein coupled receptor 52
Ligand
BDBM652359
Substrate
n/a
Meas. Tech.
Glosensor cAMP assay
EC50
278±48 nM
Citation
 ZHOU, J; ALLEN, JA; WANG, P; FELSING, DE HETEROCYCLIC G-PROTEIN-COUPLED RECEPTOR 52 (GPR52) AGONISTS US Patent  US20240059655 Publication Date 2/22/2024 
Target
Name:
G-protein coupled receptor 52
Synonyms:
G-protein coupled receptor 52 | GPR52_MOUSE | Gpr52
Type:
PROTEIN
Mol. Mass.:
41353.59
Organism:
Mus musculus
Description:
ChEMBL_117396
Residue:
361
Sequence:
MNESRWTEWRILNMSSSIVNVSEHHSCPLGFGHYSVEDVCIFETVVIVLLTFLIISGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLLVGVTCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIIMIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTCFIVCLLYAPAALVVCFTYFHIFKICRQHTKEINDRRARFPSHEVEASREAGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCVCAKDQEAQDPKPRRRANSCSI
  
Inhibitor
Name:
BDBM652359
Synonyms:
US20240059655, Compound PW0867
Type:
Small organic molecule
Emp. Form.:
C22H23N3O2
Mol. Mass.:
361.4369
SMILES:
Cc1c(Nc2cc(Cc3ccccc3)ccn2)cccc1C(=O)NCCO
Structure:
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